My husband and I spent an awful lot of $$ using Mangosteen daily for at least 8 months. I drank it with some pomegrante juice and Chris added it to his smoothies. We noticed nothing... We also donate $ to Nutrition Action and receive their periodical, they recently had an article that basically called the whole mangosteen movement a brilliant marketing scheme. We finished the bottle we had and have not bought more and again noticed no great (or minor) changes.... That being said, I believe that the only way to *know* is to try it yourself. I'm currently trying "oil pulling" to see for myself... If I can find th article, I will post some quotes.