Thanks for the info!

You are NOT nuts.

In the tabulations that follow, reported adverse events were classified using a standard
COSTART-based Dictionary terminology. The frequencies presented, therefore, represent the
proportion of the 4174 patients exposed to multiple doses of either formulation of venlafaxine
who experienced an event of the type cited on at least one occasion while receiving venlafaxine.
All reported events are included except those already listed in Table 1 and those events for which
a drug cause was remote. If the COSTART term for an event was so general as to be
uninformative, it was replaced with a more informative term. It is important to emphasize that,
although the events reported occurred during treatment with venlafaxine, they were not
necessarily caused by it.

Events are further categorized by body system and listed in order of decreasing frequency using
the following definitions: frequent adverse events are defined as those occurring on one or more
occasions in at least 1/100 patients; infrequent adverse events are those occurring in 1/100 to
1/1000 patients; rare events are those occurring in fewer than 1/1000 patients.

Body as a whole—Frequent: chest pain substernal, neck pain; Infrequent: face edema,
intentional injury, malaise, moniliasis, neck rigidity, pelvic pain, photosensitivity reaction,
suicide attempt; Rare: appendicitis, bacteremia, carcinoma, cellulitis, withdrawal syndrome.

(NOTICE THEY ARE CLAIMING WITHDRAWAL IS RARE!!!!!)

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Cardiovascular system—Frequent: migraine; Infrequent: angina pectoris, arrhythmia,
extrasystoles, hypotension, peripheral vascular disorder (mainly cold feet and/or cold hands),
syncope, thrombophlebitis; Rare: aortic aneurysm, arteritis, first-degree atrioventricular block,
bigeminy, bradycardia, bundle branch block, capillary fragility, cerebral ischemia, coronary
artery disease, congestive heart failure, heart arrest, mitral valve disorder, mucocutaneous
hemorrhage, myocardial infarct, pallor.
Digestive system—Frequent: eructation; Infrequent: bruxism, colitis, dysphagia, tongue
edema, esophagitis, gastritis, gastroenteritis, gastrointestinal ulcer, gingivitis, glossitis, rectal
hemorrhage, hemorrhoids, melena, stomatitis, mouth ulceration; Rare: cheilitis, cholecystitis,
cholelithiasis, hematemesis, gastrointestinal hemorrhage, gum hemorrhage, hepatitis, ileitis,
jaundice, intestinal obstruction, oral moniliasis, proctitis, increased salivation, soft stools, tongue
discoloration.
Endocrine system—Rare: goiter, hyperthyroidism, hypothyroidism, thyroid nodule, thyroiditis.
Hemic and lymphatic system—Frequent: ecchymosis; Infrequent: anemia, leukocytosis,
leukopenia, lymphadenopathy, thrombocythemia, thrombocytopenia; Rare: basophilia, bleeding
time increased, cyanosis, eosinophilia, lymphocytosis, multiple myeloma, purpura.
Metabolic and nutritional—Frequent: edema, weight gain; Infrequent: alkaline phosphatase
increased, glycosuria, hypercholesteremia, hyperglycemia, hyperuricemia, hypoglycemia,
hypokalemia, SGOT increased, thirst; Rare: alcohol intolerance, bilirubinemia, BUN increased,
creatinine increased, diabetes mellitus, dehydration, gout, healing abnormal, hemochromatosis,
hypercalcinuria, hyperkalemia, hyperlipemia, hyperphosphatemia, hyponatremia,
hypophosphatemia, hypoproteinemia, SGPT increased, uremia.
Musculoskeletal system—Infrequent: arthritis, arthrosis, bone pain, bone spurs, bursitis, leg
cramps, myasthenia, tenosynovitis; Rare: pathological fracture, myopathy, osteoporosis,
osteosclerosis, rheumatoid arthritis, tendon rupture.
Nervous system—Frequent: emotional lability, trismus, vertigo; Infrequent: apathy, ataxia,
circumoral paresthesia, CNS stimulation, euphoria, hallucinations, hostility, hyperesthesia,
hyperkinesia, hypotonia, incoordination, libido increased, manic reaction, myoclonus, neuralgia,
neuropathy, paranoid reaction, psychosis, seizure, abnormal speech, stupor; Rare: akathisia,
akinesia, alcohol abuse, aphasia, bradykinesia, buccoglossal syndrome, cerebrovascular accident,
loss of consciousness, delusions, dementia, dystonia, facial paralysis, abnormal gait, Guillain-
Barre Syndrome, hypokinesia, neuritis, nystagmus, paresis, psychotic depression, reflexes
decreased, reflexes increased, suicidal ideation, torticollis.
Respiratory system—Frequent: bronchitis, dyspnea; Infrequent: asthma, chest congestion,
epistaxis, hyperventilation, laryngismus, laryngitis, pneumonia, voice alteration; Rare:
atelectasis, hemoptysis, hypoventilation, hypoxia, larynx edema, pleurisy, pulmonary embolus,
sleep apnea.
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Skin and appendages—Infrequent: acne, alopecia, brittle nails, contact dermatitis, dry skin,
eczema, skin hypertrophy, maculopapular rash, psoriasis, urticaria; Rare: erythema nodosum,
exfoliative dermatitis, lichenoid dermatitis, hair discoloration, skin discoloration, furunculosis,
hirsutism, leukoderma, pustular rash, vesiculobullous rash, seborrhea, skin atrophy, skin striae.
Special senses—Frequent: abnormality of accommodation, abnormal vision; Infrequent:
cataract, conjunctivitis, corneal lesion, diplopia, dry eyes, exophthalmos, eye pain, hyperacusis,
otitis media, parosmia, photophobia, taste loss, visual field defect; Rare: blepharitis,
chromatopsia, conjunctival edema, deafness, glaucoma, retinal hemorrhage, subconjunctival
hemorrhage, keratitis, labyrinthitis, miosis, papilledema, decreased pupillary reflex, otitis
externa, scleritis, uveitis.
Urogenital system—Frequent: metrorrhagia*, prostatitis*, vaginitis*; Infrequent: albuminuria,
amenorrhea*, cystitis, dysuria, hematuria, female lactation*, leukorrhea*, menorrhagia*,
nocturia, bladder pain, breast pain, polyuria, pyuria, urinary incontinence, urinary urgency,
vaginal hemorrhage*; Rare: abortion*, anuria, breast discharge, breast engorgement, breast
enlargement, endometriosis*, fibrocystic breast, calcium crystalluria, cervicitis*, ovarian cyst*,
prolonged erection*, gynecomastia (male)*, hypomenorrhea*, kidney calculus, kidney pain,
kidney function abnormal, mastitis, menopause*, pyelonephritis, oliguria, salpingitis*,
urolithiasis, uterine hemorrhage*, uterine spasm.*