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Im totally fascinated by this cactus and am thinking of making a journey down to baja california this summer. Has anyone ever been? Any tips or other resources you know of on the web to help logistically prepare for this journey or any other cactus hunting experience in mexico?
Here's a some info on the cactus if you are interested...
www.azarius.net/news.php
www.plantconsciousness.com/sacr...s.htm
Here's a some info on the cactus if you are interested...
www.azarius.net/news.php
www.plantconsciousness.com/sacr...s.htm
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Re: Pachycereus Pringlei
Wed, March 8, 2006 - 5:47 AMThis is the only site I've found the Pachycereus Pringlei:
www.getnet.net/~richarde/...og.htm#pL22
Has anyone shopped here before?
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Re: Pachycereus Pringlei
Wed, March 8, 2006 - 6:05 AMNever mind, I've found lots of site... : )
Anyone have a favorite site for purchasing live, whole cacti?
Also, does anyone know what False Saguaro means?
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Re: Pachycereus Pringlei
Wed, March 8, 2006 - 7:26 AMFalse saguaro would be a reference to the Pachycereus resembling a giant saguaro. I have a rooted specimen I got in a trade last year, slow grower, plus they are expensive when purchased as large 5ft+ specimens. -
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Unsu...
Re: Pachycereus Pringlei
Wed, April 19, 2006 - 2:43 PMhe mentioned this at the whisteler con years ago... seem interesting.
he mentioned that there was quinoline based maois in T. bridgessi as well that explained for its low amount of mescaline and its super high effecs from a small amount of cacti. i think if bridgessi and this saguaro are mixed with another sanpedro it could possibly dramaticly increase the effects, just an idea neverr tried it.
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Unsu...
Re: Pachycereus Pringlei
Wed, April 19, 2006 - 3:02 PMwww.ethnogens.com/saguaro.html
good god the freaking jack pot here...you know i am getting pretty good at finding shit online...
www.dfranch.com/source/sag...forsale.php
www.dfranch.com/source/sag...forsale.php
www.ethnobotany-australia.net/php....php
jesus and even ebay lol!!!!
cgi.ebay.com/CARDON-MEXI...cmdZViewItem
i think someone needs to go down there harvest and sell some dry flesh. that i cant find...
man i wish i could retire in arizona right now! lake havasu is looking pretty good! -
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Re: Pachycereus Pringlei
Sat, April 22, 2006 - 12:37 PMI remember doing some reading about this one. If I remember correctly, it contains several types of phenethylamines. I've wanted to try it for a couple years now. -
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Re: Pachycereus Pringlei
Sat, April 22, 2006 - 12:57 PMChapter two of a personal research booklet I pass out to people from time to time for free. If anyone can help by finding information on the total alkaloid content of this Pachycereus Pringlei please fill me in...
2) Cacti-
"Live your life so that the fear of death can never enter your heart. When you arise in the morning, give thanks for the morning light. Give thanks for your life and strength. Give thanks for your food and for the joy of living. And if perchance you see no reason for giving thanks, rest assured the fault is in yourself."
--Chief Tecumseh, 1768-1813 Shawnee Indian Chief
"Ever since the arrival of the first Europeans in the New World, Peyote has provoked controversy, suppression, and persecution. Condemned by the Spanish conquerors for its 'satanic trickery', and attacked more recently by local governments and religious groups, the plant has nevertheless continued to play a major sacramental role among the Indians of Mexico, while its use has spread to the North American tribes in the last hundred years. The persistence and growth of the Peyote cult constitute a fascinating chapter in the history of the New World - and a challenge to the anthropologists and psychologists, botanists and pharmacologists who continue to study the plant and its constituents in connection with human affairs... How old is the Peyote cult? An early Spanish chronicler, Fray Bernardino de Sahagún, estimated on the basis of several historical events recorded in Indian chronology that Peyote was known to the Chichimeca and Toltec at least 1890 years before the arrival of the Europeans. This calculation would give the 'divine plant' of Mexico an economic history extending over a period of some two millennia. Then Carl Lumholtz, the Danish ethnologist who did pioneer work among the Indians of Chihuahua, suggested that the Peyote cult is far older. He showed that a symbol employed in the Tarahumara Indian Peyote ceremony appeared in ancient ritualistic carvings preserved in Mesoamerican lava rocks. More recently, archaeological discoveries in dry caves and rock shelters in Texas have yielded specimens of Peyote. These specimens, found in a context suggesting ceremonial use, indicate that its use is more than three thousand years old."
From: The Plants of the Gods
There are many cacti of entheogenic and historic interest. These, being found mostly in the deserts of the south and southwestern United States. Ironically, where they grow is one of the most intolerable and militant nations against entheogens on earth. These cacti include, but are not limited to: Lophophora Williamsii, L. Diffusa, L. Fricci, and Ariocarpus Retusus, A. Fissuratus, and Trichocereus Pachanoi, T. Peruvianus. & Pelecyphora Aselliformis. Each with its own unique chemical profile much like an entheogen fingerprint. Not only do these different combinations allow for easy profiling of the alkaloid extracts; they alter the overall psychedelic experience considerably. Therefore experimentation with combinations of these plants should be avoided to all except maybe the few who are mentally, physically, and spiritually ready.
The primary chemicals of interest in cacti are from the phenethylamine (PEA) family. These chemicals include the naturals like mescaline and its close relatives, of which you will soon see; and the man mades such as MDMA, MDE, the 2c series like 2c-t-7 and 2c-t-2, etc etc...
"Phenethylamines are a class of compounds chemically, and functionally, related to adrenaline -- the fight or flight neurotransmitter made from the amino acid tyrosine. Phenethylamines all contain a benzene (C6H6) ring linked to an ethylamine (-CH2-CH2-NH2) group, and include: amphetamine (a stimulant), ephedrine (a naturally-occurring decongestant), and methylenedioxymethamphetamine (MDMA, a psychotherapeutic agent that facilitates communication)...Studies in the last few years have established that phenethylamines can undergo redox cycling, a ping pong-like process that liberates copious quantities of oxygen free radicals. Free radicals are substances with extra, unpaired electrons, whose characteristic is reactivity, and whose hallmark is cell biochemical and cellular damage. Indeed, oxygen radicals are linked to a wide variety of diseases and conditions, including heart disease, stroke, cancer, emphysema, and neurological disorders. While our body has mechanisms to protect against the steady-state levels of radicals, excessive amounts overwhelm the protective systems and damage ensues. Incidentally, free radicals are not always the bad guys; our white blood cells produce, and use, free radicals as the primary means of killing bacteria, viruses, and other microbial invaders... Phenethylamines are stored in highest concentrations in the brain and nervous system. Not surprisingly, these tissues are at the greatest risk for being harmed by free radicals (and associated oxidants) formed during the redox cycling of phenethylamines. Moderate intakes appear to be handled well. Excessive quantities of phenethylamines, however, may cause oxidative damage, as the protective mechanisms just can't handle the load. It is the overproduction of radicals that causes, in large part, the fatigue and mental dysfunction associated with sustained amphetamine abuse. The key, as always, is protection, and knowing the mechanism of action can only yield one conclusion: those who take phenethylamines should also take antioxidant supplements. "
From: The Journal of Optimal Nutrition
(They make mention in the above article of how our immune system uses free radicals to destroy bacteria, coincidentally this may explain the Native Americans proven claims that Peyote works as an antibiotic medicine on the immune system.) Truly, PEAs are more closely related to dopamine but some do a great deal of their work through the adrenal system. Each of these PEAs has a slightly different threshold dose. So as you may hear me say many times- caution is to be exercised. To give you a better understanding of each plants distinct effect, later in this chapter I will list each plant mentioned above with its known phenethylamine/chemical profile. You will easily be able to see why L. Williamsii is the most valued.
The general dose for peyote (L.Williamsii) is 6-8 harvested caps or buttons, depending on size. The approximate dose for San Pedro is a kilogram. You can harvest the peyote button without killing the plant if you are careful and not greedy. Use a very sharp and sterile knife to cut the button off of the carrot-like tap root. These plants, all cacti, grow very slowly and it can easily be a decade before a peyote plant is ready for harvest. Remember that when you go to harvest an endangered plant, especially from the wild. Also, several Indian tribes warn of the experiences of some of these plants. None are for the faint of heart and some are worse than others. Dosage varies from species to species and even from individual plant to plant.
The law is sketchy on Peyote. The only cactus that is scheduled is L. Williamsii itself. Even it is legal in several states to members of the Native American Church and/or organizations like The Peyote Way Church of God. I urge you to learn as much as you can on the subject and if you have an interest to contact these organizations. See how you may join and help to preserve this most sacred plant from the near extinction that ignorant people have forced it into. Collections can be grown from seed or cuttings and requires patience and love either way. The best soil for cacti is a mostly sand to sandy-loam. It must be well draining. Over watering or cold temperatures can be damaging; a combination of the two can be fatal.
Lophophora williamsii-
3,4-dihydroxy-5-methoxyphenethylamine
3,4-dimethoxyphenethylamine
3-demethylmescaline
3-hydroxy-4,5-dimethoxyphenethylamine
3-hydroxy-4-methoxyphenethylamine
4-hydroxy-3-methoxyphenethylamine
5-hydroxy-3,4-dimethoxyphenethylamine
Anhalamine
Anhalidine
Anhalinine
Anhalonidine
Anhalonine
Anhalotine
Candicine
Hordenine
Isoanhalamine
Isoanhalidine
Isoanhalonidine
Isopellotine
Lophophorine
Lophotine
Mescalotam
Mescaline (3,4,5-trimethoxy-phenethylamine)
Mescaline citrimid
Mescaline maleimid
Mescaline sukcineimid
Mescalinisocitrimide lactone
N,N-dimethyl-3-hydroxy-4,5-dimethoxyphenethylamine
N,N-dimethyl-4-hydroxy-3-methoxyphenethylamine
N-acetyl-3-demethylmescaline
N-acetylanhalamine
N-acetylanhalonine
N-acetylmescaline
N-formyl-3-demethylmescaline
N-formyl-o-methylanhalonidine
N-formylanhalamine
N-formylanhalinine
N-formylanhalonidine
N-formylanhalonine
N-formylmescaline
N-methyl-3-hydroxy-4,5-dimethoxyphenethylamine
N-methyl-4-hydroxy-3-methoxyphenethylamine
N-methylmescaline
N-methyltyramine
Pellotine
Peyoglunal
Peyoglutam
Peyonine
Peyophorine
Peyoruvic acid
Peyotine
Peyoxylic acid
Tyramine
Dopamine
Epinine
O-methylanhalonidine
Lophophora diffusa-
Hordenine
Pellotine
Anhalinine
Anhalonidine
Isopellotine
N-methylmescaline
Mescaline
O-methylpellotine
Lophophora fricii-
6,7-dimethoxy-1,2-dimethyl-8-hydroxy-THIQ
3,4,5-trimethoxy-PEA (mescaline)
Ariocarpus retusus-
Hordenine
N-methyltyramine
N-methyl-3,4-dimethoxyphenethylamine
N-methyl-4-hydroxyphenethylamine
N-methyl-4-methoxyphenethylamine
Retusin (3,3,4,7-Tetramethoxy-5hydroxyflavone)
Ariocarpus fissuratus-
Hordenine
N-methyltyramine
N-methyl-3,4-dimethoxyphenethylamine
Trichocereus pachanoi-
3-methoxytyramine
3-demethylmescaline
3-hydroxy-4,5-dimethoxyphenethylamine
3,4-dimethoxyphenethylamine
3,4-dimethoxy-5-hydroxyphenethylamine
3,5-dimethoxy-4-hydroxyphenethylamine
4-hydroxy-3-methoxyphenethylamine
Anhalonidine
Anhalinine
Hordenine
Mescaline
Tyramine
Pellotine
Trichocereus peruvianus-
Tyramine
3-Methoxytyramine
Mescaline
2-chloromescaline
3-4-dimethoxyphenethylamine
4-hydroxy-3-5-dimethoxyphenethylamine
Pelecyphora aselliformis-
Anhalidine
Hordenine
Tyramine
N-methyltyramine
Phenethylamine
N-methylphenethylamine
4-methoxyphenethylamine
N-methyl-4-methoxyphenethylamine
3,4-dimethoxyphenethylamine
N-methyl-3,4-dimethoxyphenethylamine
Mescaline
N-methylmescaline
Pellotine
N,N-dimethyl-3-hydroxy-4,5-dimethoxyphenethylamine
3-dimethyltrichocereine
"The white man goes into his church house and talks about Jesus; The Indian goes into his teepee and talks to Jesus."
--J. S. Slotkin
8000 BC
Peyote rituals are traced back to the mescal bean ceremony of the northern native American tribes. It is the seed of the Sophora secundiflora tree. This is one of the few things that bloom in that desert climate. This seed carried lethal consequences when misused. It's use however, is much the same as what peyote was to be used for. As an oracle to forsee resolutions to troubles ahead. One quarter to one half seed would be roasted by the fire until yellowish brown. It was then consumed causing a sleepy delirium that lasted three days. The mescal bean is not to be confused with Peyote, or the mescal plant which is a Maguey (source of pulqua liquor).
4000 BC
Peyote is first isolated as the divine cactus when engulfed by a legend that dates to this time. The legend tells of a lost starving man who comes across this plant. The plant beckons for the man to eat him telling him that it is good and should be eaten. He eats the bitter, foul tasting flower and regains his strength. The man returns to his village bearing the plant and telling of his experience.
1300 BC
Engraved stone carvings of a figure holding Cacti were found in Chavin, Mexico.
1000 BC
Archeologists find evidence of peyote ceremonies dating back at least 3000 years. Specimens are found in dry caves and rock shelters as far north as Texas. These buttons are still found to be psychoactive.
700 BC
A ceramic snuffing pipe in the form of a deer with a Peyote in its mouth was found in the Oaxaca region of Mexico. In the Huichol culture, deer, maize and Peyote form a holy trinity.
200 BC
Suggestions lead to the cultivation of San Pedro as a crop in Peru at around this time.
Circa 1500
An early spanish chronicler by the name of Fray Bernardino de Sahagun finds that the Chichimeca and Toltec Indians used Peyote at least 1890 years before the arrival of the Europeans. Sahagun lived with and studied the indigenous Indians from 1499 to 1590.
15th-17th Century
Persecution of Peyote began soon after the Spanish invaders conquered the indigenous peoples. The European ecclesiastics were very intolerant of any cult but their own and soon tried to crush native beliefs, subjecting the Indians to unspeakable tortures and acts of barbarism.
The Spanish oppressor engaged in an orgy of unparalleled destruction, burning thousands of Aztec documents and other items.
To the narrow, christian minds of the invaders, Peyote was associated with the bloody Aztec sacrificial rites and condemned as Riaz diabolica (the Devils root). Several seventeenth century Jesuit priests stated that the Indians used Peyote medicinally and ceremonially. They reported that the inebriated Indians would see terrible visions.
When the hysteria of witchcraft peaked in Europe, it was not long till it spilled over into the conquered territories. In an all too familiar attempt by the Church to break the will of the people, the Holy Office of the Inquisition imposed the first drug law in the new world.
Peyote was formally denounced as an act of superstition on June, 29th 1620 as a source of divining, and foretelling future events. The Spanish persecutors, under the aegis of the Catholic Church, made every effort to totally stamp out Peyote use, subjecting the Indians to floggings, beatings, cruel tortures and even death if they persisted. One account states that as a continuation of three days of torture, a disobedient Indian had his eyes gouged out. The self-righteous Spanish then cut a crucifix into the flesh of his chest, and turned loose starving dogs to dine on his innards. They then went to church because they were devout christians.
18th Century
As late as 1760, the Catholic church still equated Peyote with cannibalism. Some of the questions asked of converts was, hath thou eaten of the flesh of man? Hath thou eaten of the flesh of Peyote? Dost thou suck the blood of others? Dost thou call upon demons for aid?
After bearing two centuries of savage oppression, and the decimation and breakup of mesoamerican civilization, the Peyote ritual was driven underground, to be silently preserved in the Chihuahuan desert. No anthropologists ever bothered to investigate or observe a Peyote ritual until well in the 1960's.
It is believed that the contemporary ceremonies of the Huichol, Cora, Yaqui, Tepecano and Tarahumara are close to the original format used during pre-Columbian times. Traditionally, Peyote has been used to treat ailments, in shamanic rituals, and even in games. The Tarahumara consume Peyote prior to engaging in 20 or 40 mile long foot races.
19Th Century
Modern scientific pharmacological studies of Peyote started in the late 1880's. In 1887, Parke Davis & Co. began to distribute dried Peyote buttons. In 1888, botanist Paul Hennings published a report on Lophophora chemistry, leading to other investigations. The principal active ingredient (mescaline) was first isolated in 1897 by a German chemist, A. Heffter. In 1892, the German explorer Lumhotz described ceremonial Peyote use among the Huichol and Tarahumara, and sent samples to Harvard for Botanical analysis.
During the later part of the 1800's, at the close of the Indian wars, Indians brought back knowledge of Peyote from raids on Mexico. As a part of the ghost dance, Peyote use spread quickly among the Indian tribes of America after 1880. Indian prophets like Quanah Parker added Christianity to traditional beliefs and formed the basis of the Peyote ritual practiced today.
20th Century
Ernst Spath was the first person to create mescaline synthetically, in his laboratory in 1919. The last extensive study of mescaline's effects was Der Meskalinrausch ( The Mescaline High), published in 1927.
Studies of Peyote and mescaline lay almost dormant until Aldous Huxley experimented with it in 1953, and later wrote The Doors of Perception. This controversial book sparked a mass of interest, helping start the Psychedelic revolution.
In 1945, scientists discovered that Cacti other than Peyote (Lophophora Williamsii) contained mescaline when San Pedro (Trichocereus Pachanoi) was found to be used by Indians of Ecuador. In 1950, Tricocereus pachanoi was analyzed and discovered to contain 1 - 2% mescaline, dry weight.
Mescaline was used around this time in early experiments into chemically induced psychosis, hence the archaic name of hallucinogens developed, psychotomimetic.
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Unsu...
Re: Pachycereus Pringlei
Tue, April 25, 2006 - 12:51 AMblah your writeing this your self? this is great stuff. i recognize alot of your refferrances. really good work! -
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Re: Pachycereus Pringlei
Wed, April 26, 2006 - 9:03 AM"blah your writeing this your self? this is great stuff. i recognize alot of your refferrances. really good work!"
It's really more a collection of research notes with some of my own stuff and thoughts. It's like a crash course in mind altering/medicinal plants that I give to people who like to learn. I've only got 22 chapters in rought draft so far though. Don't worry, I don't plan to publish and it's just to help people out.
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Unsu...
Re: Pachycereus Pringlei
Tue, April 25, 2006 - 5:29 PMso what i gather from sasha and earl is that earl took 18in of cutting and boiled it down in a 3 gallon pot for 7 hours and drank about a cup of it or maybe 3/4 a cup. i ordered some off Ebay of all places today we will see how it goes later this summer. 51$ for a 21 inche potted plant. not bad really. -
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Re: Pachycereus Pringlei
Wed, April 26, 2006 - 9:08 AM"a 21 inche potted plant."
Make sure you cut off the top 5-6 inches and pot it in sandy soil. Most cacti will take from a tip cutting very easily. -
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Unsu...
Re: Pachycereus Pringlei
Wed, April 26, 2006 - 11:17 AMsounds like a plan.... i may not plant the tip though............. -
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Re: Pachycereus Pringlei
Thu, April 27, 2006 - 3:04 PMWhat's it shaped like? I can understand where you're coming from about the root may be better than the tip. Really though most cacti and all succulents are very easily propagated by cuttings. :-) -
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Unsu...
Re: Pachycereus Pringlei
Thu, April 27, 2006 - 3:10 PMi got an email back from the grower. he said he had neverr heard of it growing from a cutting. he has only heard of it growing from seed, it seeds like crazy!
i dont see why it wouldnt take from a cutting though? he said they grow really fast from seed in arizona where he lives. but then again he has the right enviroment. he said he gets a good 6 inches in a season which isnt too bad..
i put some picks of adults on the photo list here really pretty picks...
blessings
LLB -
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Re: Pachycereus Pringlei
Thu, April 27, 2006 - 6:20 PMFucking WOW. That's huge man. I'd bet a 12 inch tip set a couple inches deep in sandy loam soil would root as a cutting in the shade. How much of this stuff do you need by volume again? You'll have to update me on the experience with it too. I'm curious. -
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Unsu...
Re: Pachycereus Pringlei
Thu, April 27, 2006 - 10:11 PMthe man said he took 18inches and boiled it in a 3 gallon pot for 7 hours... and drank a tea cup full. thats all i know... but its just enough to work with... -
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Unsu...
Re: Pachycereus Pringlei
Thu, April 27, 2006 - 10:18 PMi just have to say there is something extremely fascinating and exciteing about working with a lost entheogen...
i felt the same way with cebil snuff. i am sooo fascinated... -
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This is the maximum depth. Additional responses will not be threaded.Unsu...
Re: Pachycereus Pringlei
Fri, April 28, 2006 - 6:58 PMi just got my pachycerus pringlei in the mail today! its the size of my leg!! and as thick as my theigh. its seriously beautifull.
i dont think i will be cutting into it any time soon, its like love at first sight... you know i have to say my love for cacti grows stronger every day and with every entheogenic cacti i meet, i fall head over heal (pun intended) with it. its not fair for them up here in the PNW i know... i will either have to move down south or build a real nice green house!
but man its real purty... -
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Re: Pachycereus Pringlei
Fri, April 28, 2006 - 8:59 PMWhen I work with San Pedro, I always make sure to propagate the tip so that I don't actually destroy the life of the plant. I wish I has better access to it. My collection is pretty small at this point. Now you've got me all curious. I'm interested in sampling an alkaloid extract. Do you have any descriptions on the type of experience it is- mellow, speedy, scary? -
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Unsu...
Re: Pachycereus Pringlei
Fri, April 28, 2006 - 10:58 PMsaveing the tip and cultivating it is a good idea. i am alittle hesitant to take a cutting from it though just because its sooooo fat! its nothing like a sanpedro. and its so pretty i dont want to disfigure it. not to mention that you might need a saw to cut through the core, its hard like wood.
i might go to mexico or have a buddy down in san deigo to go and get some... but you know you can order a cactus real cheap.
all i know about the experince i have heard was from earl at the sacred elixer conferance. sounds like wonderfull! : ) -
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Re: Pachycereus Pringlei
Sat, April 29, 2006 - 7:15 AM"all i know about the experince i have heard was from earl at the sacred elixer conferance. sounds like wonderfull! : )"
Can you expand on that, even if by private message?
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Unsu...
Re: Pachycereus Pringlei
Sat, April 29, 2006 - 1:03 PMjust listen to the sound bites here...
www.plantconsciousness.com/medi...1.mp3
www.plantconsciousness.com/medi...2.mp3 -
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Unsu...
Re: Pachycereus Pringlei
Sat, April 29, 2006 - 5:31 PMThanks for posting the links. I couldn't make it and have really wanted to hear this. And yeah, it's a big cactus...
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Unsu...
Re: Pachycereus Pringlei
Tue, May 2, 2006 - 7:07 PMI'm hopeful this medicine is here for a long time, but here's a little caution for the wind:
www.bashanfoundation.org/cardo...n.html -
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Unsu...
Re: Pachycereus Pringlei
Tue, May 2, 2006 - 7:22 PMits very easy to cultivate from seed. and will grow very easily in desert climates. i am cultivaing one here in washington right now, happy and healthy, it was growing from seed in arizona. as i said they grow really fast from seed, and the adults produce insane amounts of seed each year through the fruits. cultivation of this giant of the entheogen world will be a snap in new mexico texas and arizona. out door cultivation is also very simple in these areas.
if people begin to go to baja to harvest cuttings this will not significantly disturb or disrupt the ecology of the plant itself. they are extremly hardy, growing very quickly my grower said 6 inches in a summer in arizona. they also are home for many animals they take alot of abuse from little desert critters and i think that even if it becomes popularized the cuttings and home propigation will continue to keep this cactus here with us on earth.
its the developers that need a strict talking to! -
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Re: Pachycereus Pringlei
Tue, May 9, 2006 - 5:33 PMOK... I just got done listening to Pt. 1 of the "A new elixir" lecture. I'm already hooked and feel a calling. That's unusual that I feel drawn to a plant so quickly but it's something about the way in which the guy speaks of it..... I feel a need for a specimen in my collection. -
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Unsu...
Re: Pachycereus Pringlei
Tue, May 9, 2006 - 6:03 PMi know what you mean! since i heard it and got my own cacti and looked at the magnificant phots of it in baja i am just like a little kid totaly fascinated. i really havent felt this way in years, its like a combo of lustfull infatuation and the draw to explore new mysteries like i did when i was a 19 and first gettting into all this stuff really seriously!
i was thinking yesterday dreamily about going down there and scouting the area out as well as doing some bioassys. the neat thing about this cactus is that its totaly legal. there is no known illicit compounds in it at all no mescaline nothing.
what i was thinking of was something earrl kinda mentioned in passing about setting up a retreat center in baja based around it.
i was thinking why not!? its so close to the boarder, way closer then peru or boliva or brazil and the neat thing is there are no cultural left overs attributed to it any more so to speak, its sort of wide open for rediscovery. you could theroreticaly speaking of coarse set up a center there to teach the basics of entheogenic shamanism. teach a broad perspective, givieng people the skills to learn how to work with others in a healing session with the cacti but with a intention to show them how to move that awareness to any medicine they work with at home. you could get guests down there and have it be an alternative to the brazilian center that Ott and some of the other more famous people are working at. proceeds of the center could go to helping local people and protecting the cactus forest lands the cactus live on from development by buying the land and keeping it protected in land trusts.
a school for neo-curenderismo. food made from the cactus its self could be served as well.. all kinds of ideas were running through my head...
could be really a really gratifing way to live your life... -
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Re: Pachycereus Pringlei
Wed, May 10, 2006 - 5:34 PM"what i was thinking of was something earrl kinda mentioned in passing about setting up a retreat center in baja based around it.
i was thinking why not!? its so close to the boarder, way closer then peru or boliva or brazil and the neat thing is there are no cultural left overs attributed to it any more so to speak, its sort of wide open for rediscovery."
I hear you and I'm with you but you would have to set yourself up as a 501c3 church before you even begin to think about ceremonies on any scale. Otherwise it will bring down the hammer of fascism in the matter of a year or two. We can bring back to life the ancient traditions of the native church of the cave. We would have to do our part to make sure it is farmed for the future though. It would be a very bad thing to go down there and depopulate the wonderful majestic 100 year old beauties. -
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Re: Pachycereus Pringlei
Sat, May 13, 2006 - 5:48 PMWhoa... talk about an amazing expanding idea from this tribe/post! It'll take me hours to mull over all the information here... just want to say thanks for the inspiration!
I'm working on research about the Native American Church and their use of peyote as a sustainable sacrament. It is very interesting you talk about legal US ceremonies and native traditions. Can you expand on any knowledge you have of Pachycereus Pringlei used in spiritual ceremonies in Baja??!!
Thanks!
KC -
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Re: Pachycereus Pringlei
Sat, May 13, 2006 - 5:56 PMA few months back, I was involved in an extensive peyote tribe discussion about peyote and wheter or not it is an endangered species/sacrament. A founding member of the Peyote Way Church (AZ) is the main informant in the discussion. She is a very approachable person with a lot of information to share. Please see the peyote tribe for our conversation. This provides much information regarding the current legal status of peyote, and the legal use of peyote by the NAC in the USA. -
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This is the maximum depth. Additional responses will not be threaded.
Re: Pachycereus Pringlei
Sat, May 13, 2006 - 6:34 PMAnn Camp? Seems to be the name to comes to mind. Am I close? -
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Unsu...
Re: Pachycereus Pringlei
Sat, May 13, 2006 - 6:45 PMblah - yeah, that's her.
Kim - You can hear what little is known about this new (to us) medicine on the mp3's at this site:
www.plantconsciousness.com/sacr...s.htm -
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Unsu...
Re: Pachycereus Pringlei
Sat, May 13, 2006 - 10:32 PMthere isnt much known on the traditional work with the plant the culture that worked with it is extinct. listen toearls mp3 on the subject. -
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Re: Pachycereus Pringlei
Sun, May 14, 2006 - 7:37 AMWe should bring it back but we need first to file for 501c3 before we even begin to build. I was raised in a metal fabrication shop and I'm a carpenter by trade. I can lay tile and paint too. I'll help you guys build a church if you're willing to see this thing through. I have many skills but I have zero funding. I bet I could even find skilled friends who would help. Let's do more than just let this be a passing thought. -
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Unsu...
Re: Pachycereus Pringlei
Sun, May 14, 2006 - 8:59 AMYes, this topic should not be taken lightly. I need to first do ceremony with this medicine and see what it tells me. But it's definitely calling me towards Baja at the moment.
I too have little funds and lots of skills ;)
In Lake'ch,
H- -
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Unsu...
Re: Pachycereus Pringlei
Sun, May 14, 2006 - 12:34 PMit would be very possible to start a church based around the cardon, there are no illegal compounds in it, but it could become there after. but we would either have to be a church based in the south west where the cactus can be gown easily espeicaly out doors.in the ground. i think it would be a great idea. but wee still need some more bioassys from this one... we also need some bioassays from the cacti in cultivation and see if there is a differance. -
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Re: Pachycereus Pringlei
Sun, May 14, 2006 - 3:10 PMIf it was enough to bring Dr. Shulgin into the lecture, I'm fairly confident in starting in on this without even having yet tested it. I wish to test it soon myself but should we expect a "church" to stand up against the christian fascist juggernaut of amerika, we need to start with 501c3 before doing anything else. We need a lawyer to set that into motion. If we aren't a legal church first, public ceremonies will bring the attention of the juggernaut. -
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Unsu...
Re: Pachycereus Pringlei
Sun, May 14, 2006 - 3:21 PMi agree the 501c3 is the essential first step blah.
it does seem that this would be the best canidate for a new entheogen church becuase it has no illicit compounds and the cactus cannot be called a container for mescaline ect... it might fall under the analog law becuase there are PEAs that make it active but it sounds its mostly the cardonine thats is the active isoquinoline in it. if this is true they would have to have an emergancy schedualing of it, like they are trying with salvia, but if we establish a church and a doctorine first and for most it wont be too much of an issue.
i know a guy in santa fe who started an ayahuasca vine church, just the vine, and its combined with paganism, iteresting idea. you can see his web page here...
www.padeva.com/
cool site. i like the cover page art alot...
at any rate we should discuss this with the peyote way people see if they have some advice. but also we should think about how it is to be set up, autonomous chapters around the usa with a loose non dogmatic practice would be nice differant chapterrs doing it differantly, all with a central theme though. -
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Re: Pachycereus Pringlei
Sun, May 14, 2006 - 3:27 PMYes, I have contacted padeva for info and we should ask Anne for council. I think we could beat the fascist states of amerika in the race on this one because, as far as I can tell, they haven't even caught wind of it. We neeeeed an established 501c3 fast. That's the keystone of this church idea. If we grandfather ourselves in, even if they outlaw it, we will have the grandfather clause of the official church.
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Re: Pachycereus Pringlei
Sun, May 14, 2006 - 3:30 PMWe would need a central physical structure to, at the very least, be an official farm. We can't take take take from such a majestic plant without giving back. That's not to say we couldn't also make sure the surrounding hills don't get populated with other useful cacti. -
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Unsu...
Re: Pachycereus Pringlei
Sun, May 14, 2006 - 3:40 PMmy group has thought about the chursh thing quite alot as well. i really like the idea, all you need is a place that can be a public meeting ground. i beleive it has to be a structure that is "open" to the public. what else do you need a doctorine? -
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Unsu...
Re: Pachycereus Pringlei
Sun, May 14, 2006 - 6:02 PMI'll start bouncing this idea off of a few people around here and see what they say. I have a few connections that might be able to help a bit with the legal aspects of starting a church.
I guess I better burn a few mp3's of the conference and get a few baby cactii to hand out to people.. hehe -
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Re: Pachycereus Pringlei
Sun, May 14, 2006 - 7:11 PMI offer up my skills, labor, and love. I really have nothing else to give. I really would love to see this religion/ceremony brought back to life in its proper context. I'm already dreaming on it and that's unusual. I rarely get all worked up over a plant like this. I feel a calling for this cave as well. I was always interested in geology when I was a young kid and had the biggest rock collection of anyone I ever met. It's funny how two of my life's passions have surfaced now entwined. -
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 12:30 AMwww.mulege.net/latrinidad.htm
www.mulege.net/sanborjitas.htm
www.bajaquest.com/cavepaintings/
here are some pics of the cave painting he saw...
today i looked up realestate prices in the town he was in mulege pretty good prices 60,000 for a 13 acear ranch is pretty good. i was thinking you could grow cardon and sell it to the ethnobotnaical trade or you could set up tours like with the ayahuasca tourism in peru. -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 6:27 AMi havent read or listened to all the post, links in this thread yet ,but before ya'll go and start a church you need to find out if this cactus is gonna kill anyone.im also very intrested in this cactus and am contemplating buying my own.what happened to the indians that once used this cactus? did they all have strokes and die?maoi's and phenethylamines dont mix. well...they do but its not healthy.i'm looking foward to LLB'S experience.be careful fellow sykonauts. -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 7:39 AM"what happened to the indians that once used this cactus?"
They most likely moved on due to a drought of some sort or were killed off by a rival tribe in the area. Entheogen type drugs have a way of making people more peaceful. It wouldn't surprise me if, having grown up in Tx, Apache or Comanche bands passed through there at one point and just overtook them. Those two tribes were regularly at war with someone.
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 8:21 AMBio-assay's are definitely needed. I will be seeing a friend of mine on Thursday who spoke at the Sacred Elixers conference and plan on having a serious conversation with him about this. He's an expert on on Soma and Tibet and has a lot of knowledge about lost religion. He was the one who told me about the Cardon Medicine before the conference even happened. So, like I said, I'm going to bounce this idea off of a few people and see what happens. I'm also going to try and find a baby in one of the local nurseries today. Wish me luck! -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 9:51 AMGood luck. I'd bet this is a plant that would take very well from tip cuttings too. I have a really green thumb but plants like that don't need much attention. Just cut the top 6 inches off and place it about 2 inches into sandy soil and the plant does the rest.
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 12:20 PMIt seems there are already plenty of tours to the various archeological sites. Also, a couple of the sites are on private property. But there doesn't seem to be anyone doing healing tours. That might be our ticket.
Here's a cool tidbit I found: Each year, on the winter solstice, the sun comes into the cave and illuminates directly and exclusively the eyes of “El Diablito”.
I am also fascinated by the fact that most of the images are painted in red and black (two out of my three favorite colors). Check out the pic I posted of "El Diablito".
Hmm... This all seems so natural to me......... -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 12:41 PMWe would need to set this up on private property so some would have to be aquired or we would need someone sympathetic to the idea who owns the property already. A 501c3 on private property would be near untouchable by law. -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 1:03 PMI just sent an Email to see if I can hook up with you guys for the Mesa project. Let's see what the local guy says. -
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 1:59 PMyou need to listen to the whole speach by shulgin on this one skull farmer. its not like other maois its not a betacarboline either its an isoquinoline called cardonine and its unique to this cacti. T bridgessi aslo has maoi isoquinolines in it as well which explains why its so active and has such low mescaline content. there are many things that act as a maoi in relation with another substance and there are maois that effect or target certian things and not others. what your thinking about is verry differant then what we have here in this cactus. the natural occuring isoquinoline based maois in cardon as well as other cacti will not cuase any hypertension when combined with the other PEAs in the cacti. its pretty damn safe. its probably pretty safe to assume that there are isoqunolines in most psychoactive cacti that act as a sort of maoi and that this just has not really been looked at before. isoquinolines are very potent in small amounts, and occur in cacti in verry small amounts.. when somee one is doing gas chromography to detirmine the alkaliod content of these plants, the big spikes are normaly focused on as the bioactive chemicals the little spikes are not normaly thought or or focused on becuase its rare that the littel spikes are bioactive. this was the case with the isoquinolines they have been realativly over looked in ethnopharmacology until now. i got to see shulgins little speach on this at the whisteler conferance. i think i might have a recording of it still. and he discusses this to some degree on the sacred elixers mp3 file. listen to the whole thing.
there is no need to be alarmed. -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 2:26 PMsounds intresting.i plan on reading all the links 2nite, hopefully.
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 5:33 PM"there is no need to be alarmed."
You said my feelings exactly. I got the same take on it from listening to Sasha's SE talk. It does seem that there have been a lot of alkoloids have been overlooked and deserve closer inspection. IMHO I think we've just touched the tip of the iceberg. -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 5:55 PMAlso, as I feel has been overlooked as a subtopic, is the process digestion itself. What one chemical starts out as may not be psychoactive but pass it through the stomach and liver then BANG- you never know what you got and there is a bit of recycling that goes on in the blood before we expel urine.... eh, just a thought. Each cactus is also full of several to dozens of substances that work as a synergy. Also thinking about the chemical process of digestion... could maybe one or more of these alkaloids be concocted into something else midway through the system? -
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 6:11 PMgod what was so interesting was shulgins funny little pill he had which was cardonine and a PEA ( a legal one) combined what did he call it? pharmacactihuasca silly bugger!
what i am still really interested in is wether or not these isoquinolines in cardone and achuma will work to potentiate peas in other cacti, such as just plain sanpedro, or some other pea like a research chem like 2ci it could very easily and safely potentiate any pea, with out cuaseing the unpleasent effects of maoi from a potential dangerous betacarboline addative. -
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Re: Pachycereus Pringlei
Mon, May 15, 2006 - 6:20 PMI'm curious as to what a cup of brew would be like if your raw material was 50/50 San Pedro and P. Pringlei. That would really be something right there.
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 6:21 PMYes, Pharmahuasca. I've had the opportunity to do ceremony with it here in the Bay Area a few times. I passed on it though since I didn't feel ready for it at the time. I haven't heard of it in a few years though. -
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 6:37 PM"I'm curious as to what a cup of brew would be like if your raw material was 50/50 San Pedro and P. Pringlei. That would really be something right there."
yeah thats what i am wondering! curenderos often add differant plants as well as cacti to sanpedro or cimora mixtures to stregthen its effects...wait a minute what if some of the admixtures that are traditionaly used in cimora that are cactus based addmixtures have maoi isoquinolines? huh....something to think about...
but yeah i am thinking that small amounts of either T. bridgessi or cardone could be added to the relatively weak T. pachanio or peruvianus brews, as a stregthening addmixture so that not to much had to be used of either.... could it be that we have found the cactus worlds equivilency of caapi and rue? -
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Unsu...
Re: Pachycereus Pringlei
Mon, May 15, 2006 - 6:39 PMi am getting giddy again...this cacti has done that quite a bit and i still havent tried it yet! -
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Unsu...
Re: Pachycereus Pringlei
Tue, May 16, 2006 - 1:12 AMholy mary mother of god! check this out!!!
www.loretobay.com/cms/page1114.cfm
i found this on tribes actualy as one of thier adds!
its in Baja! and its one of the towns with tons of cardon in it!!!
one of the worlds largest sustianable communties!!!! -
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Re: Pachycereus Pringlei
Tue, May 16, 2006 - 4:11 AMawesome
this is very exciting
thereis some great info here
i will be speaking with some local cactoi collectors trying to source some plants definately worth having in the collection
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Unsu...
Re: Pachycereus Pringlei
Tue, May 16, 2006 - 7:23 AMCool, now I need to somehow triple my economy so that I can buy one of those places. Hmmm.... maybe a retirement place for my father... He does love Mexico.... Wow, I have so much to talk about at my sister's weekly potluck on Thursday... Gotta keep the ball rolling on this one!
btw - no luck finding a baby Pachy yesterday. I'll try some other places today.
Also - I talked to a friend yesterday (who's an ordained minister) about the church set-up and she referred me to the Center for Cognative Liberty and Ethics and specifically her lawyer (Richard Glen Boire). Mr. Boire does a lot of work in the direction we are thinking of going in. It sounds promising. Check out their site here: www.cognitiveliberty.org/ -
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Re: Pachycereus Pringlei
Tue, May 16, 2006 - 7:39 AMCCLE sounds promising and they may actually be interested in this one. You work on it then because your connections seem to be tighter there than mine are. I've known and gathered info from them for years though. -
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Unsu...
Re: Pachycereus Pringlei
Tue, May 16, 2006 - 2:02 PMcheck out ebay for baby cardon seriously thats where i got mine. -
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Unsu...
Re: Pachycereus Pringlei
Wed, May 17, 2006 - 2:18 AMthis has just come to my attention...
mdma.net/alexander-shu...ofessor-x.html
QUOTE
JUST AFTER sunset on a cool California evening last fall, Alexander Shulgin prepared to test the effects of the cactus Pachycereus pringlei on himself, his wife, and 10 other subjects. The group, which included two chemists and an anthropologist, gathered in the living room of a redwood house deep in the woods to help Shulgin with his research into psychedelic cacti. A few months earlier, the anthropologist had told Shulgin that this particular variety was worth looking into - a cave painting in Mexico suggested it might have psychoactive properties. Through chromatography, Shulgin determined that P. pringlei probably was a mild psychedelic, but "the establishment of its human pharmacology requires that it be consumed by man." So Shulgin dissolved the extract of the cactus into fruit juice, then poured a 4-ounce cup for each person. But his experiment went awry. "At about the two-hour point, my visual experiences became totally swamped by an overwhelming fear of moving," recalls Shulgin, the 77-year-old chemist who introduced ecstasy to the world. His wife, Ann, had an even more severe reaction. Out on the deck, she remembers, "I could see the full moon shining down on me with what felt like chilling contempt, and I thought, What an awful, stupid way to die." With her pulse racing, she went inside to check on her husband, who was upstairs in one of the bedrooms, lying still in the dark. "He said he was OK as long as he didn't move." Early the next morning, Shulgin assembled his test group, still in pajamas, to assess the effects of the cactus extract. All 12 of them had taken the same compound, but half had become violently ill, while the other six had the kind of pleasant but unremarkable experience Shulgin expected. The results, he decided, were inconclusive.
the fact that he doesnt mention this at all in his latest speach on the subject has me confused. this was done 2 years ago and the sacred elixers conferance was what this year? -
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Re: Pachycereus Pringlei
Wed, May 17, 2006 - 4:24 AMi wonder if there is a way you can contact shulgin and ask directly
cna you still ask question on that site called ask shulgin, or whatever it is?
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Unsu...
Re: Pachycereus Pringlei
Wed, May 17, 2006 - 7:52 AMDidn't Earl give a similar account of an earlier experience in his talk? And in his talk, Sasha mentions that he tried a little bit and it didn't do anything. Interesting....
Maybe they're trying to keep it under wraps because they're going to start their own Curch of Cardon? <g> -
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Re: Pachycereus Pringlei
Wed, May 17, 2006 - 8:06 AMMaybe there was a mixup in species? I still think there's promise for this plant, especially when combined with other cacti. -
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Re: Pachycereus Pringlei
Wed, May 17, 2006 - 10:00 AMwhat about L. diffusa? it contains a hint of mes and some isoquinolines. anyone ever try this cacti? -
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Unsu...
Re: Pachycereus Pringlei
Wed, May 17, 2006 - 10:40 AMNo, I haven't but would like to. Have you been able to find L. diffusa available in the US? -
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Re: Pachycereus Pringlei
Wed, May 17, 2006 - 12:00 PMI've seen it on Ebay occasionally and it's legal in the US.
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Re: Pachycereus Pringlei
Thu, May 18, 2006 - 10:04 AMAnn Zapf...
A founding member of the Peyote Way Church, AZ.
Amazing woman. -
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Re: Pachycereus Pringlei
Fri, May 26, 2006 - 6:34 PMthere is another thread here somewhere on the shulgin announcement from the conference. i will try to dig it up.
i also posted several links in that thread to info relating to Pachycereus Pringlei.
my family is driving baja all the time so i was very keen to find out the possibilities!
I believe that the alkaloid content was insufficient to really produce any strong effects.
i will look for the links again. -
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Re: Pachycereus Pringlei
Fri, May 26, 2006 - 6:39 PMit's all blocked at work, and i think Tribe done chopped the thread i was thinking of. here is the full article from sacred elixir conference:
Professor X
Alexander Shulgin made millions for Dow Chemical. Then he synthesized MDMA, realized his best test subject was himself, and became the godfather of Generation Ecstasy.
Now he's back inside his private lab, running a new batch
of psychedelic compounds through his chromatograph.
By Ethan Brown
JUST AFTER sunset on a cool California evening last fall, Alexander Shulgin prepared to test the effects of the cactus Pachycereus pringlei on himself, his wife, and 10 other subjects. The group, which included two chemists and an anthropologist, gathered in the living room of a redwood house deep in the woods to help Shulgin with his research into psychedelic cacti. A few months earlier, the anthropologist had told Shulgin that this particular variety was worth looking into - a cave painting in Mexico suggested it might have psychoactive properties. Through chromatography, Shulgin determined that P. pringlei probably was a mild psychedelic, but "the establishment of its human pharmacology requires that it be consumed by man." So Shulgin dissolved the extract of the cactus into fruit juice, then poured a 4-ounce cup for each person. But his experiment went awry. "At about the two-hour point, my visual experiences became totally swamped by an overwhelming fear of moving," recalls Shulgin, the 77-year-old chemist who introduced ecstasy to the world. His wife, Ann, had an even more severe reaction. Out on the deck, she remembers, "I could see the full moon shining down on me with what felt like chilling contempt, and I thought, What an awful, stupid way to die." With her pulse racing, she went inside to check on her husband, who was upstairs in one of the bedrooms, lying still in the dark. "He said he was OK as long as he didn't move." Early the next morning, Shulgin assembled his test group, still in pajamas, to assess the effects of the cactus extract. All 12 of them had taken the same compound, but half had become violently ill, while the other six had the kind of pleasant but unremarkable experience Shulgin expected. The results, he decided, were inconclusive. Such unorthodox experiments are common for Shulgin, who might be described as practicing hard science with a blurry edge. With his gray beard, shock of white hair, and wrinkled tribal-patterned shirts, he certainly looks the part of a counterculture icon. But unlike Timothy Leary or Terence McKenna, Shulgin doesn't proselytize for psychedelic drugs. Instead, he invents new compounds, runs experiments to determine their pharmacological effects, and publishes his recipes. His 1976 synthesis of MDMA (3,4-methylenedioxymethamphetamine), aka ecstasy, is the best-known result of his work. But he's also created dozens of other psychoactive compounds, including DOM (2,5-dimethoxy-4-methylamphetamine), more commonly known as the potent '60s psychedelic STP, and 2C-T-7 (2,5-dimethoxy-4-(n)-propylthiophenethylamine), now sold on the street as "tripstasy"and suspected in the overdose death of a Tennessee teenager last year. Together with Ann, Shulgin has written two books that have become cult classics: PIHKAL: A Chemical Love Story (short for "Phenethylamines I Have Known And Loved") and TIHKAL: The Continuation (about tryptamines). They have long tested his compounds on themselves, in the tradition of scientists a century ago, then written about them in a style that mixes dispassionate technical detail ("A suspension of 9.5 g LAH in 750 ml well stirred and hydrous Et20 was held at reflux under an inert atmosphere") with wide-eyed psychedelic utopianism ("I saw the cloud toward the west. THE CLOUDS!!! No visual experience has ever been like this."). His approach inspired the so-called psychonauts, a small group of scientifically sophisticated young explorers who post chemical syntheses, experimental results, and "Train Wrecks and Trip Disasters" at Erowid.org. "Shulgin has given the scientific approach a role model," says one psychonaut who, under the pseudonym Murple, self-publishes studies on next-generation psychedelics like 2C-T-7.
Shulgin's experiment with P. pringlei is part of his most ambitious project yet - to classify the psychoactive compounds that occur naturally in cacti. Hundreds of plants have such properties, but many have never been tested, and Shulgin's search to identify the effects of each have drawn him to botany guides, anthropology books, and ancient religious texts. He plans to publish his results in 2004, and the anticipation is such that online sites catering to the psychonaut scene have begun to sell the plants he's working with.
"I really appreciated what morphine did. It depersonalized the pain."
To these psychedelic adventurers, Shulgin is a postmodern Prometheus bearing the gift of chemical enlightenment. Even some scientists who speak out against drugs see value in his work: "There are merits to what Shulgin is doing, as the government does not allow real, unbiased studies with psychedelic drugs," says Jonathan Porteus, a psychologist at Cal State Sacramento who works with clients experiencing memory and mood problems as a result of ecstasy use. But to antidrug crusaders, Shulgin is a Frankenstein who has loosed frightening pharmacological monsters on the youth of the world. When Shulgin was invited to speak at a conference on drug policy in England, the head of an antidrug group said it was like "going to an asylum and asking the inmates about mental health."
THE SHULGINS live in the hills of Lafayette, California, on a 20-acre ranch at the end of a winding dirt driveway that's been called Shulgin Road since the chemist's parents purchased the land in the '30s. It's a sunny summer day, and Ann sets out a plate of hummus and fruit on the patio. Then she thrusts out a story about Shulgin from Britain's Daily Mail headlined "HAS THIS MAN KILLED 100 BRITISH TEENAGERS?" "We're not sure if we want this interview to happen," she says coolly, gesturing at the article like it's a piece of evidence. "What kind of knowledge of psychedelics do you have?" She means personal experience. Finally, she allows, I can start asking questions, "but I'll put up a red a flag if you're inappropriate."
In the Shulgins' kitchen, a homey room decorated with a lifetime's worth of counterculture souvenirs - art by a peyote-worshiping tribe, a photo of Shulgin with New Age nutrition guru Andrew Weil - I ask the obvious question: How does he feel now that ecstasy has become an international phenomenon - and, to some, an international scourge? "It's pretty heavy-duty," Shulgin says solemnly. "I don't think it's being used the way it should." He disapproves of the potentially dangerous doses clubbers often take, and he worries that recreational use of his drugs will overshadow their higher purpose. Psychedelics are a means for adults to gain insight into themselves, Shulgin says. "The best words I can use are research tools."
Speak for yourself, Sasha," Ann interjects, using her husband's nickname. "I like to turn on and observe the universe. Scientists try to explain that these drugs aren't for fun as if there's something wrong with fun." The divide between the Shulgins reflects the schism between those who see psychedelics as a way to expand the senses and those who see them as a method to unlock the mind. While ravers gobble pills with abandon, psychonauts carefully measure out their desired dose.
Shulgin says ecstasy is particularly good for breaking down personal barriers, which is why some therapists used it before it was made illegal. "You don't have that sense of psychic territory to keep a psychiatrist out of," he says.
To Shulgin, a self-proclaimed libertarian, publishing synthesis instructions is "totally responsible": "If you're going to make a drug and use a drug, you want accurate information." A regular reader of the Federal Register, Shulgin even has a legal argument. "If you look at the Constitution, the 10th Amendment says anything that isn't handled in the Constitution or mentioned in the previous nine amendments should be reverted to the people or the states." In any case, he says, the government has no business making laws about personal behavior.
What about driving under the influence, Ann asks. Bad driving itself should be illegal, Shulgin replies - whatever its cause.
In the study that adjoins the kitchen, Ann's 36-year-old daughter, Wendy, is helping Shulgin research adrenochrome, an oxidized version of adrenaline briefly in vogue in the early '70s thanks to a mention in Hunter S. Thompson's Fear and Loathing in Las Vegas. Medical studies have linked an excess of adrenochrome to brain dysfunction, and Shulgin believes the chemical could help scientists understand schizophrenia. "I've found a book on Amazon, but it's $75," Wendy shouts. "I need your credit card." Shulgin rises from his chair. "Take two," he says to her, pulling out his wallet, "$50 on one and $25 on the other."
The Shulgins can come across like a psychedelic version of the Osbournes - an ambling, eccentric paterfamilias, a kid who's caught up in the family business, and a savvier, more aggressive wife who protects them from the outside world. "Sasha made a decision a long time ago that he would never sell any drug," Ann says forcefully. Indeed, Shulgin has never played a role in getting any of the chemicals he's created onto the street. "As far as I know," he says at Ann's prompting, "I'm not doing anything illegal."
In fact, Shulgin has some establishment leanings. He belongs to the elite, all-male Bohemian Club (Dick Cheney and George Shultz are members), and in 1988 he published Controlled Substances: A Chemical and Legal Guide to the Federal Drug Laws. In one of the more ironic moments of the war on drugs, he and Ann were married on their ranch on July 4, 1981, by the administrator of a DEA lab he was friendly with. Exactly one year later, the man held his wedding in the same spot. Shulgin never had a problem with the law until 1994, when the drug agency raided the lab behind his house. He wasn't charged with anything, but he surrendered the DEA-approved analytical license that allowed him to study certain scheduled drugs. (A spokesperson for the agency's San Francisco office would not comment on the raid.) "The issue is closed, and I have the freedom of doing whatever lab work I choose," Shulgin says. Nevertheless, "the separation between me and my friends at the DEA is now quite severe."
BORN IN BERKELEY to two public-school teachers, Shulgin was raised in an intellectual atmosphere, and he was just 7 when he first wandered into the local chemical supply store. "It was a 15-minute bicycle ride from my house," he remembers, "and I'd go there and say, 'I'd like to get some sodium bicarbonate or some magnesium sulfate.' They'd take a glassine bag and put some chemicals in it and there was no charge. Today there would be regulations against that."
An apt student who mastered two foreign languages (Russian and French) and three instruments (violin, viola, and piano), Shulgin entered Harvard on a full scholarship in 1942. "It was a total, total disaster," he recalls. "The people around me were sons and daughters of important people, with money and property, position and stature. I was not, and there was no social blending at all." In the middle of his sophomore year, he dropped out to join the Navy.
Shulgin was stationed on a destroyer escort in the North Atlantic during World War II, and he remembers being shocked by all the death he saw around him. He was never hurt badly, but the treatment he received for a painful infection introduced him to a lifelong fascination. "I really appreciated what morphine did," he recalls. "It doesn't quiet the pain - it makes you indifferent to it. It depersonalizes the pain."
Shulgin got an honorable discharge in 1946 and enrolled at UC Berkeley to study chemistry. He received his PhD in biochemistry in 1954, and the spirit of intellectual openness was an important influence. He wrote a letter to the head of the chemistry department at the University of Pennsylvania suggesting a more efficient way to synthesize morphine. "I got an answer," he remembers. "He said, 'Neat idea - it's never been tried.' Even if he didn't say much, he acknowledged the letter. To me, that was a great treasure."
Ever since, Shulgin has endeavored to answer all his mail, and he runs an Internet forum called "Ask Dr. Shulgin," in which he fields questions on such esoteric topics as the interaction of peyote with antidepressants. Murple recalls sending Shulgin an entire unsolicited manuscript of a book he was working on and receiving a detailed response.
After graduating from Berkeley, Shulgin took a job with a clinical diagnostics company, but he quickly jumped to Dow Chemical, where he invented Zectran, the first biodegradable insecticide. Still fascinated by mind-altering substances, he tried mescaline in 1960 and was moved to begin researching psychoactive drugs. "It was given to me by a psychiatrist friend, and it was the turning point that dictated the direction of my research for the rest of my life," he says. "I was confronted with the reality that the drug wasn't doing anything - it was just the catalyst. How much else was in there that I had no access to?"
Shulgin spent the next few years tinkering with the molecular structure of mescaline, inventing DOM and a few other compounds that, through the actions of others, ended up in the Haight-Ashbury and, soon after, in the Controlled Substances Act of 1970. Dow wasn't happy with this research, but since Zectran had proven profitable, he was granted time to work on his pet projects - from home. "Dow said, 'Do as you wish,'" Shulgin recalls. "I did as I wished. I did psychedelics."
ECSTASY was first synthesized in 1912 by the pharmaceutical company Merck, which used it as a chemical intermediary. It wasn't administered as a psychoactive substance until 1953, when the US government tested it on animals as a possible chemical warfare agent. Shulgin created a new synthesis for MDMA on September 12, 1976, according to his journal, and he told Wired he was tipped off to its possible effects by an undergrad in a medicinal chemistry group he advised at San Francisco State University. At the time, MDA (3,4-methylenedioxyamphetamine), dubbed "Mellow Drug of America," was popular on the psychedelic scene, and the student mentioned having heard something about its methylated version.
Shulgin first tried 16 milligrams of MDMA to no noticeable effect (the average dose in a pill is 75 to 150 milligrams), then upped the amount incrementally every week. At 81 milligrams, he had his eureka moment. "First awareness at 35 minutes smooth, and it was very nice," Shulgin wrote in his journal. "Forty-five minutes still developing, but I can easily assimilate it as it comes under excellent control. Fifty minutes getting quite deep, but I am keeping a pace."
"MDMA didn't have the tremendous effect on him that it did on other people," Ann says. For her, the compound is "an extraordinary opener. There's no other drug that gives you such consistent insight." Ann began administering MDMA to people as a sort of lay-therapist. Shulgin introduced the drug to Leo Zeff, an Oakland psychologist who guided dozens of his patients through sessions on various drugs. (Zeff himself viewed psychedelics as a path to enlightenment and wrote about dancing with a Torah while tripping on LSD.) Zeff was so enthusiastic about the compound that he postponed his retirement to travel across the country introducing MDMA to hundreds of his fellow therapists. Along the way, he gave the drug its first street name, Adam, because he believed it stripped away neuroses and put users in a primordial state.
Thanks to Zeff's advocacy, MDMA was widely known as an experimental therapy by the mid-'80s; Phil Donahue devoted an entire show to its medical potential in February 1985. But in Dallas, a very different use of the compound was emerging. Renamed "ecstasy" by a former drug dealer who sensed its commercial potential, MDMA was sold at nightclubs like the Starck right alongside Jack Daniel's and Bud. Months after Donahue's program aired, the DEA estimated that Dallas residents were consuming nearly 30,000 hits of ecstasy per month. Though it's sometimes difficult to pinpoint the specific cause of an overdose death in someone who has ingested multiple substances, the Dallas County Medical Examiner's Office estimated that in the early and mid-'80s, misuse of the drug had killed five people.
Among those in the psychiatric community who believed in the potential of ecstasy, some argued that therapists should administer it quietly. Others, including Shulgin, urged them to publish their results. In April 1985, MDMA was classified as an emergency Schedule 1, a drug with "high potential for abuse" and "no currently accepted medical use in treatment in the United States." (Permanent Schedule 1 status followed a year later.) Not a single therapist had published on the drug's therapeutic benefits - mostly, Shulgin says, out of fear they'd be seen as endorsing what was called the "yuppie psychedelic."
Even with his creation outlawed, Shulgin continued to make a case for its use. At a 1992 National Institute on Drug Abuse technical review on hallucinogens, Shulgin admitted testing psychoactive compounds on himself. "Sasha found a way, with DEA people in attendance, to present the results of human studies on psychedelics," says Rick Doblin, founder and president of the Multidisciplinary Association for Psychedelic Studies. "It was one of the more heroic, in-the-lion's den moments I've ever seen." Two years later, the national body issued a report stating, among other things, "there is an urgent need for human testing." This fall, Doblin will begin testing MDMA as a treatment for post-traumatic stress disorder, the first FDA-approved psychotherapy research into the drug since it was criminalized.
AFTER A LUNCH of homemade pepperoni pizza, Shulgin leads me down to his lab on a hay-strewn path flanked by Salvia divinorum, an herb used by shamanic healers in Oaxaca, Mexico. On the door, a heavy, printed sign reads THIS IS A KNOWN AND APPROVED RESEARCH FACILITY; a smaller placard displays the international symbol for radioactive material, and a third lists a local contact number for the DEA. A harsh chemical odor wafts out when he opens the door. On one wall, there's a torn, browning copy of the periodic table; against another, shelves hold beakers containing bits of dissected cacti.
HE POINTS TO THE GRAPH: "BINGO! WE�VE GOT ACTIVITY."
"How does one know if a certain cactus is active?" Shulgin asks. There's often anthropological evidence that a plant is psychoactive, but many species have several names, while even experts have a hard time distinguishing between various types of cacti. Several that contain psychoactive material, including Trichocereus pachanoi, more commonly known as San Pedro, are sold at garden centers.
When questions of taxonomy arise, Shulgin isolates and identifies specific compounds through chromatography. "Here I'm totally caught up in the Western tools of science," he says, as classical music blares from a transistor radio hanging from a ceiling beam. "Get a bit of plant into the test tube, shove the wet residue into the chromatographic monster, and you discover 20 new things in the plant." He shows me a small notebook with pages displaying the peaks and valleys of printed-out chromatography. "Bingo!" he says, pointing to an upward shift. "We've got activity."
That's where the standard scientific method ends. Shulgin will sample an extremely low dose with Ann, then bring the substance to the group with whom he tried P. pringlei. Sometimes his psychedelic adventures scare him, Shulgin says, "but how else are you going to learn?" In case the worst does happen, "I always keep an anti-convulsant on hand."
These days, though, the group doesn't meet as much anymore. "We're getting too old," he says.
SHULGIN RARELY travels, but he's come to MIT for an American Chemical Society symposium on "The Chemistry and Pharmacology of Hallucinogens." During a wine and cheese reception before dinner, he's mobbed by chemistry students, who thrust out dog-eared copies of PIHKAL for him to sign. One tells Shulgin that he took a bus all the way from Indiana just to meet him. A Goth couple persuades him to pose with them for a few Polaroids.
In a crisp white shirt and blue-striped tie, Shulgin looks like an overwhelmed teenager forced to dress for some family function. During the presentations, several lecturers mention his work, and a researcher from the National Institute on Drug Abuse refers to a few psychedelics as "Shulgin analogs."
"Where are my dirty pictures?" Shulgin asks Ann in a panic. He means the transparencies he's made of the chemical structures of his compounds. Moments later he finds them in the knapsack he left by the bar and enlists me to keep track of his materials.
Shulgin is more at ease when the conference breaks for dinner, riffing on palindromes (his favorite is Soros), his views on drug laws (to prove a point, he pulls out a wallet-sized copy of the Constitution), and the asparagus ("Everyone check their urine later and let me know if it smells").
After dinner, as the sun sets over the Charles River, Shulgin steps behind the podium and explains some of his syntheses at such dizzying speeds that he has to stop a few times to catch his breath. As his creations are projected behind him, he talks about the hand-drawn diagrams of MDMA, MMDA, and 2C-T-7 the way anyone else might talk about photos of their vacation or wedding.
"It's the excitement of discovering something totally unknown," he tells me later.
"I feel an incredible tingle when I look at a white solid I've just synthesized that I know has never existed anywhere in the universe before this moment." He stops himself. "Oh, maybe someone on a planet around some sun way out there may have looked at it, but this is its first existence on Earth. And I'll be the first to know what it does." -
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Unsu...
Re: Pachycereus Pringlei
Fri, May 26, 2006 - 7:17 PMthis experiment of his was a few years prior to the sacred elixers conferance. i find it interesting that shulgin didnt mention any of this at the sacred elixers mp3. its also interesting that he says he mixed an extract in the juice. and extract mixed in juice doesnt sound like a tea made from the cacti, maybe i am wrong. but perhaps an extract was what he used and it was not the way to go.
i have read this before and i have foudn that what this says compaired to the MP3 is just wierd.
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Unsu...
Re: Pachycereus Pringlei
Fri, May 26, 2006 - 6:56 PMi think you might be surprised as top how strong it might be. from what earl said it seems like it it pretty good. -
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Re: Pachycereus Pringlei
Fri, May 26, 2006 - 7:28 PMRandom thoughts: Different parts of the growth of a cactus will have different alkaloid profiles. The fleshy green new growth could be very different from the woody older growth. who knows what parts which researcher was working with? I think a 50/50 with San Pedro would be something to be reckoned with. Anyway, I think this new entheogen needs to be further examined and worked with. Also a dissolved alkaloid extract can be a very different experience than a boiled down organic preparation... I had the same reaction to 5-meo-DMT that Ann had to this cactus the first time I tried it but I would regret never having tried it again, especially from natural sources. The first time I did it, it was synthetic white powder. In fact, I still have a healthy respect, almost fear, of 5-meo-DMT. -
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Unsu...
Re: Pachycereus Pringlei
Sat, May 27, 2006 - 12:12 AMdad allways preached a healthy fear of god....
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Re: Pachycereus Pringlei
Sat, May 27, 2006 - 11:05 AMi feel the same about 5-meo .still having a couple hundred mgs but dread stepping back into the void.the day will come when my intrest peaks for it again,but im not sure it will be anytime soon after my last trip with it.
with 20mgs, all the lights out,in total darkness,with no sitter i thought i had died until i came to on the bathroom floor 20min later.when i came to the lights were on halfway thru the house but i dont remember turning them on.i thought someone had come into my house and found me like that until i got up and couldnt find anyone.thats givin me plenty respect for it.it reminded me of a strong salvia dose. -
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Re: Pachycereus Pringlei
Fri, June 9, 2006 - 4:54 PMi finally made it through this whole thread!
land is very cheap in Baja, and the cardon is everywhere.
i would love to find a space in the mountains south of la paz.
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Re: Pachycereus Pringlei
Sun, October 19, 2008 - 4:27 PMAll sounds quite interesting, any experiences with this since the last post? Thanks